The Japanese Journal of Clinical Oncology (JJCO) was established in 1971 by Dr. Masaru Kuru, the third President of the National Cancer Center (NCC) and also first Director of the National Cancer Center Hospital, who felt at that time a strong need for an international journal of clinical oncology from Japan. For the first 10 years after its establishment JJCO was a biannual journal. After steady growth in the number of both papers and subscribers, it became quarterly in 1983 and bimonthly in 1991, publishing original articles, reviews, case reports and epidemiological notes. Its emphasis is on publishing case reports and clinical investigations with various clinical implications, even when they represent negative results. The journal also encourage those authors who are working on frontier subjects to put forward their views, even when they do not have enough data to confirm their ideas.