Editor(s): Felix Mitelman
Impact Factor: 3.696
Genes, Chromosomes & Cancer offers rapid publication of original full-length research articles, perspectives, reviews, and letters to the editors, as well as editorial commentaries on genetic analysis as related to the study of neoplasia.
Particular emphasis is placed on work combining molecular and cytogenetic analyses of the genomic alterations of cancer cells. Insights into basic biologic mechanisms or the clinical management of neoplastic disorders are also included.
Specific areas covered include:
-- Chromosomal abnormalities in all benign and malignant disorders, including changes that occur during neoplastic progression
-- Changes in gene structure and regulation as a consequence of genomic rearrangements
-- Chromosomal alterations involving genes related to the regulation of cell proliferation and differentiation
-- The correlation between genomic abnormalities and cellular phenotypic alterations
-- The predictive value of alterations at the chromosomal and DNA levels in disease prognosis, and in designing and monitoring cancer therapies
-- Cytogenetic, molecular, and epidemiologic analyses of inherited disorders predisposing to cancer
-- Chromosomal and/or genetic damage caused by external factors
-- Descriptions of novel molecular biological and cytogenetic methods for genomic analysis