Evaluation of the rapid Quidel Sofia Lyme fluorescent immunoassay as a first-tier test in a modified 2-tier testing algorithm for Lyme disease

A comparison with the Zeus ELISA Borrelia VlsE1/pepC10 lgG/IgM assay followed by the Zeus monovalent IgM/IgG confirmatory assay

Lee-Lewandrowski, Elizabeth PhD, MPH
Turbett, Sarah MD
Branda, John A MD
Lewandrowski, Kent MD

Department of Pathology, Division of Clinical Laboratories and Molecular Medicine, Massachusetts General Hospital
Harvard Medical School, Boston, MA, US
Department of Pathology, Division of Clinical Laboratories and Molecular Medicine, Massachusetts General Hospital
Harvard Medical School, Boston, MA, US
Department of Pathology, Division of Clinical Laboratories and Molecular Medicine, Massachusetts General Hospital
Harvard Medical School, Boston, MA, US
Department of Pathology, Division of Clinical Laboratories and Molecular Medicine, Massachusetts General Hospital
Harvard Medical School, Boston, MA, US

Corresponding author: Elizabeth Lee-Lewandrowski, PhD, MPH; [email protected].

Received May 11, 2023

Accepted July 17, 2023

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)

American Journal of Clinical Pathology 160(6):p 599-602, December 2023. | DOI: 10.1093/ajcp/aqad094