ProtTest: selection of best-fit models of protein evolution

Abascal, Federico
Zardoya, Rafael
Posada, David

¹Department of Biochemistry, Genetics and Immunology, Universidad de Vigo 36310 Vigo, Spain
²Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales 28006 Madrid, Spain

Received on October 7, 2004; revised on December 15, 2004; accepted on January 5, 2005; Advance Access publication January 10, 2005

Availability: ProtTest is available under the GNU license from http://darwin.uvigo.es

Contact: [email protected]

^*To whom correspondence should be addressed.

Bioinformatics 21(9):p 2104-2105, May 1, 2005.

Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment.