ClustalW-MPI

ClustalW analysis using distributed and parallel computing

Li, Kuo-Bin

Bioinformatics Institute, 30 Medical Drive, Singapore 117609, Republic of Singapore

Received on December 15, 2002; accepted on March 2, 2003

Bioinformatics 19(12):p 1585-1586, August 12, 2003.

Summary

ClustalW is a tool for aligning multiple protein or nucleotide sequences. The alignment is achieved via three steps: pairwise alignment, guide-tree generation and progressive alignment. ClustalW-MPI is a distributed and parallel implementation of ClustalW. All three steps have been parallelized to reduce the execution time. The software uses a message-passing library called MPI (Message Passing Interface) and runs on distributed workstation clusters as well as on traditional parallel computers.

Availability

The source codes are written in ISO C and are available at http://www.bii.a-star.edu.sg/software/clustalw-mpi/. An open source implementations of MPI is available from http://www-unix.mcs.anl.gov/mpi/.

Contact

[email protected]