Experimental Comparison of a New Intracaval Filter with the Mobin-Uddin Umbrella Device

Brown, Phillip P. M.D.
Peyton, Marvin D. M.D.
Elkins, Ronald C. M.D.
Greenfield, Lazar J. M.D.

From the Department of Surgery, University of Oklahoma Health Sciences Center, and the Veterans Administration Hospital, Oklahoma City, Oklahoma.

Circulation 50(2):p II-276, August 1974.

A new intracaval filter has been developed for transvenous insertion under local anesthesia. The conical shape of the unit permits continued flow around trapped emboli, with reduction in cross-sectional area to 49% when 70% of the cone is filled. Experimental embolization of 10 ml of autologous clot in dogs was followed by complete occlusion in 4 of 7 dogs protected by a Mobin-Uddin umbrella, with 1 early death in an additional dog after misplacement. None of the intracaval filters placed in 15 dogs were observed to occlude over a 6-week period, and all showed resolution of the trapped thrombus. Penetration of the aorta by a prong of the Mobin-Uddin umbrella was noted in 1 animal. There were no instances of migration or recurrent embolization. Preliminary clinical experience with the intracaval filter after insertion in 10 patients has shown continued patency and no recurrent emboli.