Risks in new drug development: Approval success rates for investigational drugsDiMasi, Joseph A. PhDAuthor informationBoston, MassFrom the Director of Economic Analysis, Tufts Center for the Study of Drug Development, Tufts University.Received for publication Nov 6, 2000.Accepted Feb 26, 2001.This research was supported in part by a grant from the Drug Information Association.Reprint requests: Joseph A. DiMasi, PhD, Tufts Center for the Study of Drug Development, Tufts University, 192 South St, Suite 550, Boston, MA 02111.Clin Pharmacol Ther 2001;69:297-307.Clinical Pharmacology & Therapeutics 69(5):p 297-307, May 2001.Copyright © Mosby-Year Book Inc. 2001. All Rights Reserved.