Intravenous vs. Nebulized Tranexamic Acid and Hemoptysis: Which Strategy Is Better?

Radigan, Kathryn MD

Attending Physician, Division of Pulmonary and Critical Care, Stroger Hospital of Cook County, Chicago

Critical Care Alert 31(7):p 54-55, October 2023.

SYNOPSIS: A pragmatic, open-label, randomized, parallel, single-center pilot trial investigating nebulized vs. intravenous tranexamic acid in patients with non-massive hemoptysis showed that nebulized tranexamic acid may be more effective in reducing the amount of hemoptysis and the need for interventional procedures.

SOURCE: Gopinath B, Mishra PR, Aggarwal P, et al. Nebulized vs IV tranexamic acid for hemoptysis: A pilot randomized controlled trial. Chest 2023;163:1176-1184.