Midazolam sedates agitated patients more rapidly than haloperidol-promethazineRapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.

TREC Collaborative Group. Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine. BMJ 2003; 327: 708–13.TREC Collaborative GroupRapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.BMJ2003327708-13Q Is midazolam or haloperidol plus promethazine more effective for rapid sedation of agitated or aggressive people with mental illness?

For correspondence: Dr G Huf, Universidade Federal do Rio de Janeiro, Núcleo de Estudos de Saúde Coletiva, Av. Brigadeiro Trompowsky s/n, Edifício Hospital Universitário 5 andar, ala sul - Ilha do Fundão, Rio de Janeiro, Brazil, 21941-590, Caixa Postal 68037; [email protected]

Sources of funding: no participating centre directly received funds for involvement in TREC.