Multicystic Peritoneal Mesothelioma in an Octogenarian: Diagnosis, Natural History, and Treatment

Psoinos, Charles M. BS
Kandil, Dina MD
Piperdi, Bilal MD
Lambert, Laura A. MD

¹University of Massachusetts-Memorial Medical Center, Worcester, MA, USA

Corresponding Author: Laura A. Lambert, Division of Surgical Oncology, University of Massachusetts-Memorial Medical Center, Swift House, 119 Belmont Street, Worcester, MA 01605, USA Email: [email protected]

International Journal of Surgical Pathology 20(1):p 92-96, February 2012. | DOI: 10.1177/1066896911400737

Abstract

Multicystic peritoneal mesothelioma (MCPM) is a rare cystic proliferation most often seen in women of reproductive age with a history of prior abdominal surgery. This is a case report of an 83-year-old woman diagnosed with MCPM during an exploratory laparotomy for presumed peritoneal carcinomatosis from colon cancer. After complete removal of all visible MCPM, the patient remains free of both colon cancer and MCPM. This article reviews the literature with regards to the pathology, natural history, risk of malignant transformation, and current options for management of MCPM, including cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.