A Rare Complication of Gastric Bypass (Weight Loss) Surgery: Nesidioblastosis

Ünal, Betül MD
Uzun, Özlem Ceren MD
Başsorgun, Cumhur İbrahim MD
Erdoğan, Okan MD
Elpek, Gülsüm Özlem MD

¹Akdeniz University, Antalya, Turkey

Corresponding Author:

Betül Ünal, Department of Pathology, School of Medicine, Akdeniz University, Antalya, 07070, Turkey.

International Journal of Surgical Pathology 23(1):p 68-70, February 2015. | DOI: 10.1177/1066896914554833

Abstract

Here, we present the case of a 31-year-old woman patient who underwent distal pancreatectomy with the history of gastric bypass surgery for obesity. The final histopathological diagnosis of the lesion was nesidioblastosis. Nesidioblastosis is the most common cause of organic persistent hyperinsulinemic hypoglycemia in newborns; however, it is rare in adults. In adults, it is difficult to diagnose nesidioblastosis with only clinical findings. The definitive diagnosis of the disease depends on the histopathological examination of pancreatic tissue and the exclusion of insulinoma.