From the Department of Research and Development, S Mamede do Coronado, Portugal (Dr Nunes, Dr Almeida, Mr Rocha, Mr Fernandes-Lopes, Ms Loureiro, Dr Wright, Dr Vaz-da-Silva, Dr Soares-da-Silva); Institute of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Porto, Portugal (Dr Almeida, Dr Vaz-da-Silva, Dr Soares-da-Silva); Department of Health Sciences, University of Aveiro, Portugal (Dr Almeida); and 4Health Consulting, BIOCANT, Cantanhede, Portugal (Dr Falcão). Submitted for publication February 27, 2009; revised version accepted May 10, 2009. Address for correspondence: Patrício Soares-da-Silva, MD, PhD, Department of Research & Development, BIAL, À Av da Siderurgia Nacional, 4745–457 S Mamede do Coronado, Portugal; e-mail: [email protected].
This work was supported by BIAL-Portela & Co, SA.
Financial disclosure: Teresa Nunes, Luis Almeida, José-Francisco Rocha, Carlos Fernandes-Lopes, Ana I. Loureiro, Lyndon Wright, M. Vaz-da-Silva, and Patrício Soares-da-Silva, are employees of BIAL (Portela & Ca S.A). Amílcar Falcão received a consultancy fee from BIAL for work on this study.
