Urolithiasis in Pre-Term Neonates Associated with Furosemide Therapy

Noe, Norman H.
Bryant, John F.
Roy, Shane III
Stapleton, Bruder F.

From the Department of Urology, Division of Pediatric Urology and Department of Nephrology, Division of Pediatric Nephrology, University of Tennessee Center for the Health Sciences and LeBonheur Children’s Medical Center, Memphis, Tennessee

^*Requests for reprints: LeBonheur Children’s Medical Center, 848 Adams, Suite 403, Memphis, Tennessee 38103.

Accepted February 3, 1984.

Journal of Urology 132(1):p 93-94, July 1984. | DOI: 10.1016/S0022-5347(17)49479-1

ABSTRACT

The administration of furosemide to pre-term neonates has been associated with urolithiasis. We report 1 of 2 such cases that we have managed. The etiology of these stones appears to be related to furosemide-induced hypercalciuria. Nonsurgical management with thiazide diuretics can be successful in this high risk group of patients.