The emergence of systemic lupus erythematosus in hypothyroid patients

two case reports and mini review

Bakr, A
Laimon, W
El-Ziny, MA
Hammad, A
El-Hawary, AK
Elsharkawy, AA
El-Refaey, AM
Salem, NA
El-Mougy, A
Zedan, MM
Aboelenin, HM
Eid, R
Sarhan, A

Faculty of Medicine, Mansoura University Children Hospital, Mansoura, Egypt

Wafaa Laimon, Faculty of Medicine, Mansoura University Children Hospital, Egypt. Email: [email protected]

Received August 22, 2013

Accepted February 4, 2014

Lupus 23(8):p 825-828, July 2014. | DOI: 10.1177/0961203314525866

Systemic lupus erythematosus (SLE) is a multi-systemic autoimmune disease that involves almost all the organs in the human body and is characterized by auto antibodies formation. Autoimmune thyroid diseases (AITD) are organ-specific diseases that are associated with a production of a variety of antibodies such as antinuclear antibodies, anti-double-stranded DNA, anti-Ro antibodies, anti-cardiolipin antibodies, and others. The diagnosis of AITD in patients with SLE is well known, but the reverse is rarely reported. We present two cases of adolescent girls in whom SLE evolved one year after being diagnosed with hypothyroidism.