BIOCHEMISTRY: Indifferent chaperones

Jankowsky, Eckhard

Eckhard Jankowsky is in the Department of Biochemistry and the Center for RNA Molecular Biology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. e-mail:[email protected]

Nature 449(7165):p 999-1000, October 25, 2007. | DOI: 10.1038/449999a

How do nonspecific enzymes that help to correct RNA folding identify misfolded structures among similar, properly folded RNAs? It seems that careful discrimination has little to do with it.