Gastrointestinal Angiodysplasia before and after Treatment of Severe Aortic Stenosis

  • Yashige, Masaki M.D.
  • Inoue, Ken M.D., Ph.D.
  • Zen, Kan M.D., Ph.D.
  • Kobayashi, Reo M.D.
  • Nakamura, Shunsuke M.D.
  • Fujimoto, Tomotaka M.D.
  • Takamatsu, Kazuaki M.D.
  • Sugino, Satoshi M.D., Ph.D.
  • Yamano, Michiyo M.D., Ph.D.
  • Yamano, Tetsuhiro M.D., Ph.D.
  • Nakamura, Takeshi M.D., Ph.D.
  • Doman, Tsuyoshi M.D.
  • Teramukai, Satoshi Ph.D.
  • Horiuchi, Hisanori M.D., Ph.D.
  • Itoh, Yoshito M.D., Ph.D.
  • Matoba, Satoaki M.D., Ph.D.

  • 1Kyoto Prefectural University of Medicine, Kyoto, Japan [email protected], [email protected]

    2Tohoku University, Sendai, Japan

    3Kyoto Prefectural University of Medicine, Kyoto, Japan

Supported by the Joint Research Program of the Joint Use and Joint Research Center at the Institute of Development, Aging, and Cancer, Tohoku University; the Japan Agency for Medical Research and Development (grant JP23ek0109536); and the Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research (KAKENHI ) program (grant JP21K07967).

Disclosure forms provided by the authors are available with the full text of this letter at NEJM.org.

New England Journal of Medicine 389(16):p 1530-1532, October 19, 2023. | DOI: 10.1056/NEJMc2306027

Gastrointestinal Angiodysplasia and Severe Aortic Stenosis

In a prospective study involving 50 patients with severe aortic stenosis and anemia, 94% had angiodysplasia, of whom 69% had lesions in the small intestine. After TAVR, the number and size of angiodysplastic lesions were reduced.

Gastrointestinal Angiodysplasia before and after TAVR

  • Natale, Francesco M.D., Ph.D.
  • Golino, Paolo M.D.
  • Cimmino, Giovanni M.D, Ph.D.
New England Journal of Medicine 390(1):p 95, January 4, 2024. | DOI: 10.1056/NEJMc2313153
Copyright © 2023 Massachusetts Medical Society. All rights reserved.
View full text|Download PDF