Ethics of Placebo-Controlled Trials of Zidovudine to Prevent the Perinatal Transmission of HIV in the Third World

Institut Francais de Recherche Scientifique pour le Developpement en Cooperation; 75480 Paris CEDEX 10, France (Lallemant); Harvard Medical School (McIntosh); Harvard School of Public Health; Boston, MA 02115 (Jourdain); Institut National d'Etudes Demographiques; 75675 Paris, France (Le Coeur); Chiang Mai University; Chiang Mai 50202, Thailand (Vithayasai); Harvard School of Public Health (Lee); Harvard Medical School; Boston, MA 02115 (Hammer); World Bank; Washington, DC 20433 (Prescott); Harvard School of Public Health; Boston, MA 02115 (Essex)