From the Divisions of Adolescent Medicine and Endocrinology, Children's Hospital Boston, Boston. Address reprint requests to Dr. Gordon at Children's Hospital, 300 Longwood Ave., Boston, MA 02115, or at [email protected].
An audio version of this article is available at NEJM.org.
Dr. Gordon reports being a consultant for Gilead Sciences and serving as codirector (with partial salary support) of the Clinical Investigator Training Program sponsored by the Harvard-MIT Division of Health Sciences and Technology, Pfizer, and Merck. No other potential conflict of interest relevant to this article was reported.
Disclosure forms provided by the author are available with the full text of this article at NEJM.org.
I thank Dr. S. Jean Emans for helpful discussions on this topic and on an earlier version of the manuscript.