From the Internal Medicine Service, Addiction Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain (D.F.); and the Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center and Boston University School of Medicine, the Grayken Center for Addiction, Boston Medical Center, and the Department of Community Health Sciences, Boston University School of Public Health — all in Boston ( J.H.S.).
Dan L. Longo, M.D., Editor
Address reprint requests to Dr. Samet at Boston University Schools of Medicine and Public Health, 801 Massachusetts Ave., 2nd Fl., Boston, MA 02118, or at [email protected].
No potential conflict of interest relevant to this article was reported.
Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.
We thank Richard Saitz, M.D., M.P.H., for his critical review of an earlier version of the manuscript, and Kristina King, M.P.H., for her assistance with development of earlier versions of the manuscript and figures.